In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.

Jackson, W; Hornik, CP; Messina, JA; Guglielmo, K; Watwe, A; Delancy, G; Valdez, A; MacArthur, T; Peter-Wohl, S; Smith, PB; Tolia, VN; Laughon, MM

In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.

dc.contributor.author	Jackson, W
dc.contributor.author	Hornik, CP
dc.contributor.author	Messina, JA
dc.contributor.author	Guglielmo, K
dc.contributor.author	Watwe, A
dc.contributor.author	Delancy, G
dc.contributor.author	Valdez, A
dc.contributor.author	MacArthur, T
dc.contributor.author	Peter-Wohl, S
dc.contributor.author	Smith, PB
dc.contributor.author	Tolia, VN
dc.contributor.author	Laughon, MM
dc.date.accessioned	2019-03-19T14:44:28Z
dc.date.available	2019-03-19T14:44:28Z
dc.date.issued	2017-07
dc.date.updated	2019-03-19T14:44:26Z
dc.description.abstract	OBJECTIVE:To characterize in-hospital outcomes of premature infants diagnosed with severe bronchopulmonary dysplasia (BPD). STUDY DESIGN:Retrospective cohort study including premature infants with severe BPD discharged from 348 Pediatrix Medical Group neonatal intensive care units from 1997 to 2015. RESULTS:There were 10 752 infants with severe BPD, and 549/10 752 (5%) died before discharge. Infants who died were more likely to be male, small for gestational age, have received more medical interventions and more frequently diagnosed with surgical necrotizing enterocolitis, culture-proven sepsis and pulmonary hypertension following 36 weeks of postmenstrual age compared with survivors. Approximately 70% of infants with severe BPD were discharged by 44 weeks of postmenstrual age, and 86% were discharged by 48 weeks of postmenstrual age. CONCLUSIONS:A majority of infants diagnosed with severe BPD were discharged home by 44 weeks of postmenstrual age. These results may inform discussions with families regarding the expected hospital course of infants diagnosed with severe BPD.
dc.identifier	jp201749
dc.identifier.issn	0743-8346
dc.identifier.issn	1476-5543
dc.identifier.uri	https://hdl.handle.net/10161/18165
dc.language	eng
dc.publisher	Springer Science and Business Media LLC
dc.relation.ispartof	Journal of perinatology : official journal of the California Perinatal Association
dc.relation.isversionof	10.1038/jp.2017.49
dc.subject	Humans
dc.subject	Sepsis
dc.subject	Enterocolitis, Necrotizing
dc.subject	Bronchopulmonary Dysplasia
dc.subject	Hypertension, Pulmonary
dc.subject	Patient Discharge
dc.subject	Risk Factors
dc.subject	Retrospective Studies
dc.subject	Sex Factors
dc.subject	Gestational Age
dc.subject	Infant
dc.subject	Infant, Newborn
dc.subject	Infant, Small for Gestational Age
dc.subject	Intensive Care Units, Neonatal
dc.subject	North Carolina
dc.subject	Female
dc.subject	Male
dc.subject	Infant, Extremely Low Birth Weight
dc.subject	Electronic Health Records
dc.subject	Infant, Extremely Premature
dc.title	In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.
dc.type	Journal article
duke.contributor.orcid	Hornik, CP\|0000-0001-7056-8759
duke.contributor.orcid	Messina, JA\|0000-0001-6411-198X
pubs.begin-page	853
pubs.end-page	856
pubs.issue	7
pubs.organisational-group	School of Medicine
pubs.organisational-group	Duke
pubs.organisational-group	Duke Clinical Research Institute
pubs.organisational-group	Institutes and Centers
pubs.organisational-group	Pediatrics, Critical Care Medicine
pubs.organisational-group	Pediatrics
pubs.organisational-group	Clinical Science Departments
pubs.organisational-group	Pediatrics, Neonatology
pubs.organisational-group	Medicine, Infectious Diseases
pubs.organisational-group	Medicine
pubs.publication-status	Published
pubs.volume	37

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