Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.

dc.contributor.author

Aykut, Berk

dc.contributor.author

Overbey, Douglas M

dc.contributor.author

Medina, Cathlyn K

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Omer, Tariq M

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Rajab, T Konrad

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Ngeve, Smith M

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Beckerman, Ziv

dc.contributor.author

Turek, Joseph W

dc.date.accessioned

2025-07-01T16:51:39Z

dc.date.available

2025-07-01T16:51:39Z

dc.date.issued

2025-03

dc.description.abstract

Background

Partial heart transplantation (PHT) has emerged as a pioneering approach for treating infants with irreparable heart valve dysfunction. However, the scarcity of suitable donors presents a significant bottleneck to its widespread application. This study introduces and evaluates the novel use of domino and split-root procedures within PHT.

Methods

We describe 6 pediatric cardiac patients who underwent either domino or split-root PHT at our institution.

Results

From May to August 2023, our team successfully executed 3 domino and 3 split-root PHTs, including 1 procedure that involved interinstitutional collaboration. These cases highlight the procedural feasibility and the potential for broader application.

Conclusions

The implementation of PHT represents a significant advance in pediatric heart care. Domino and split-root techniques within the PHT framework have the potential to substantially increase both donor availability and recipient capacity. These strategies usher in a new era of organ stewardship through addressing the challenge of donor organ shortage.
dc.identifier

S2772-9931(24)00359-0

dc.identifier.issn

2772-9931

dc.identifier.issn

2772-9931

dc.identifier.uri

https://hdl.handle.net/10161/32538

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Annals of thoracic surgery short reports

dc.relation.isversionof

10.1016/j.atssr.2024.07.033

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.title

Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.

dc.type

Journal article

duke.contributor.orcid

Turek, Joseph W|0000-0002-4006-7555

pubs.begin-page

86

pubs.end-page

91

pubs.issue

1

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

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Clinical Science Departments

pubs.organisational-group

Pediatrics

pubs.organisational-group

Surgery

pubs.organisational-group

Surgery, Cardiovascular and Thoracic Surgery

pubs.publication-status

Published

pubs.volume

3

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