Common data model for sickle cell disease surveillance: considerations and implications.

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults and the functional evaluation of adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

Dr. Kayle’s program of research aims to improve health outcomes among people with childhood-onset complex chronic conditions, with a focus on sickle cell disease (SCD). In partnership with the North Carolina Department of Health and Human Services, Division of Public Health, she co-leads the North Carolina Sickle Cell Data Collection Program (NC SCDC), a state-level surveillance program funded by the Centers for Disease Control and Prevention. NC SCDC curates and analyzes multi-source, population-level datasets to describe the epidemiology, health outcomes, and social determinants of health influencing SCD. Dr. Kayle collaborates with national and state partners to disseminate surveillance findings informing practice, research, and policy for SCD.

Dr. Kayle teaches Nursing Care of Infants, Children, and Adolescents in the Accelerated Bachelor of Nursing program. Her service contributions include several state-level committees on SCD.

Dr. Kayle completed her Bachelor of Science in Nursing at the American University of Beirut, her Master's in Pediatric Acute and Critical Care and her Doctor of Philosophy in Nursing at Duke University School of Nursing, and her Postdoctoral Fellowship in Health Services and Outcomes Research at Northwestern University, Feinberg School of Medicine. She has over twelve years of pediatric acute and critical care clinical experience.