Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions.

Abstract

We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify measured ARFI-induced displacements in RFA lesion and unablated myocardium and (2) calculate the lesion contrast (C) and contrast-to-noise ratio (CNR) in two-dimensional ARFI and conventional intracardiac echo images. In eight canine subjects, an ARFI imaging-electroanatomical mapping system was used to map right atrial ablation lesion sites and guide the acquisition of ARFI images at these sites before and after ablation. Readers of the ARFI images identified lesion sites with high sensitivity (90.2%) and specificity (94.3%) and the average measured ARFI-induced displacements were higher at unablated sites (11.23 ± 1.71 µm) than at ablated sites (6.06 ± 0.94 µm). The average lesion C (0.29 ± 0.33) and CNR (1.83 ± 1.75) were significantly higher for ARFI images than for spatially registered conventional B-mode images (C = -0.03 ± 0.28, CNR = 0.74 ± 0.68).

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Published Version (Please cite this version)

10.1177/0161734613519602

Publication Info

Eyerly, Stephanie A, Tristram D Bahnson, Jason I Koontz, David P Bradway, Douglas M Dumont, Gregg E Trahey and Patrick D Wolf (2014). Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions. Ultrason Imaging, 36(2). pp. 133–148. 10.1177/0161734613519602 Retrieved from https://hdl.handle.net/10161/10368.

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Scholars@Duke

Bahnson

Tristram Dan Bahnson

Professor of Medicine
Koontz

Jason Koontz

Associate Professor of Medicine

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