A pathway in primate brain for internal monitoring of movements.
| dc.contributor.author | Sommer, Marc A | |
| dc.contributor.author | Wurtz, Robert H | |
| dc.coverage.spatial | United States | |
| dc.date.accessioned | 2016-03-25T03:15:56Z | |
| dc.date.issued | 2002-05-24 | |
| dc.description.abstract | It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem to frontal cortex might carry corollary discharge signals. We found that neuronal activity in this pathway encodes upcoming eye movements and that inactivating the pathway impairs sequential eye movements consistent with loss of corollary discharge without affecting single eye movements. These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals. | |
| dc.identifier | ||
| dc.identifier | 296/5572/1480 | |
| dc.identifier.eissn | 1095-9203 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | American Association for the Advancement of Science (AAAS) | |
| dc.relation.ispartof | Science | |
| dc.relation.isversionof | 10.1126/science.1069590 | |
| dc.subject | Animals | |
| dc.subject | Brain Mapping | |
| dc.subject | Fixation, Ocular | |
| dc.subject | Frontal Lobe | |
| dc.subject | GABA Agonists | |
| dc.subject | Macaca mulatta | |
| dc.subject | Mediodorsal Thalamic Nucleus | |
| dc.subject | Muscimol | |
| dc.subject | Neural Pathways | |
| dc.subject | Neurons | |
| dc.subject | Proprioception | |
| dc.subject | Saccades | |
| dc.subject | Superior Colliculi | |
| dc.title | A pathway in primate brain for internal monitoring of movements. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Sommer, Marc A|0000-0001-5061-763X | |
| pubs.author-url | ||
| pubs.begin-page | 1480 | |
| pubs.end-page | 1482 | |
| pubs.issue | 5572 | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Biomedical Engineering | |
| pubs.organisational-group | Center for Cognitive Neuroscience | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Duke Institute for Brain Sciences | |
| pubs.organisational-group | Institutes and Provost's Academic Units | |
| pubs.organisational-group | Neurobiology | |
| pubs.organisational-group | Pratt School of Engineering | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | University Institutes and Centers | |
| pubs.publication-status | Published | |
| pubs.volume | 296 |
Files
Original bundle
- Name:
- SommerWurtz2002.pdf
- Size:
- 361.87 KB
- Format:
- Adobe Portable Document Format
- Description:
- Published version