Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery.

Passias, Peter G

Williamson, Tyler K

Kummer, Nicholas A

Pellisé, Ferran

Lafage, Virginie

Lafage, Renaud

Serra-Burriel, Miguel

Smith, Justin S

Line, Breton

Vira, Shaleen

Gum, Jeffrey L

Haddad, Sleiman

Sánchez Pérez-Grueso, Francisco Javier

Schoenfeld, Andrew J

Daniels, Alan H

Chou, Dean

Klineberg, Eric O

Gupta, Munish C

Kebaish, Khaled M

Kelly, Michael P

Hart, Robert A

Burton, Douglas C

Kleinstück, Frank

Obeid, Ibrahim

Shaffrey, Christopher I

Alanay, Ahmet

Ames, Christopher P

Schwab, Frank J

Hostin, Richard A

Bess, Shay

International Spine Study Group

2023-12-22T17:23:00Z

2023-12-22T17:23:00Z

2023-12-11

STUDY DESIGN/SETTING: Retrospective cohort study. OBJECTIVE: Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery. METHODS: ASD patients with 2-year (2Y) data were included. Tertiles were used to define high degrees of frailty, sagittal deformity, blood loss, and surgical time. Cost was calculated using the Pearl Diver registry and cost-utility at 2Y was compared between cohorts based on the number of risk factors present. Statistically significant differences in cost-utility by number of baseline risk factors were determined using ANOVA, followed by a generalized linear model, adjusting for clinical site and surgeon, to assess the effects of increasing risk score on overall cost-utility. RESULTS: By 2 years, 31% experienced a major complication and 23% underwent reoperation. Patients with ≤2 risk factors had significantly less major complications. Patients with 2 risk factors improved the most from baseline to 2Y in ODI. Average cost increased by $8234 per risk factor (R2 = .981). Cost-per-QALY at 2Y increased by $122,650 per risk factor (R2 = .794). Adjusted generalized linear model demonstrated a significant trend between increasing risk score and increasing cost-utility (r2 = .408, P < .001). CONCLUSIONS: The number of defined patient-specific and surgical risk factors, especially those with greater than two, were associated with increased index surgical costs and diminished cost-utility. Efforts to optimize patient physiology and minimize surgical risk would likely reduce healthcare expenditures and improve the overall cost-utility profile for ASD interventions.Level of evidence: III.

2192-5682

2192-5690

https://hdl.handle.net/10161/29547

eng

SAGE Publications

Global Spine J

10.1177/21925682231212966

https://creativecommons.org/licenses/by-nc/4.0

adult spinal deformity

cost-utility

major complications

mechanical failure

risk stratification

spine

surgical factors

Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery.

Journal article

Shaffrey, Christopher I|0000-0001-9760-8386

21925682231212966

Duke

School of Medicine

Clinical Science Departments

Orthopaedic Surgery

Neurosurgery

Published online