Validation of the Hebrew version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale.

dc.contributor.author

Zitser, Jennifer

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Peretz, Chava

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Ber David, Aya

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Shabtai, Herzl

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Ezra, Adi

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Kestenbaum, Meir

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Brozgol, Marina

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Rosenberg, Alina

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Herman, Talia

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Balash, Yakov

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Gadoth, Avi

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Thaler, Avner

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Stebbins, Glenn T

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Goetz, Christopher G

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Tilley, Barbara C

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Luo, Sheng T

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Liu, Yuanyuan

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Giladi, Nir

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Gurevich, Tanya

dc.date.accessioned

2019-08-01T21:09:36Z

dc.date.available

2019-08-01T21:09:36Z

dc.date.issued

2017-12

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2019-08-01T21:09:36Z

dc.description.abstract

The Movement Disorders Society (MDS) published the English new Unified Parkinson's Disease Rating Scale (MDS-UPDRS) as the official benchmark scale for Parkinson's disease (PD) in 2008. We aimed to validate the Hebrew version of the MDS-UPDRS, explore its dimensionality and compare it to the original English one.The MDS-UPDRS questionnaire was translated to Hebrew and was tested on 389 patients with PD, treated at the Movement Disorders Unit at Tel-Aviv Medical Center. The MDS-UPDRS is made up of four sections. The higher the score, the worst the clinical situation of the patient is. Confirmatory and explanatory factor analysis were applied to determine if the factor structure of the English version could be confirmed in the Hebrew version.The Hebrew version of the MDS-UPDRS showed satisfactory clinimetric properties. The internal consistency of the Hebrew-version was satisfactory, with Cronbach's alpha values 0.79, 0.90, 0.93, 0.80, for parts 1 to 4 respectively. In the confirmatory factor analysis, all four parts had high (greater than 0.90) comparative fit index (CFI) in comparison to the original English MDS-UPDRS with high factor structure (0.96, 0.99, 0.94, 1.00, respectively), thus confirming the pre-specified English factor structure. Explanatory factor analysis yielded that the Hebrew responses differed from the English one within an acceptable range: in isolated item differences in factor structure and in the findings of few items having cross loading on multiple factors.The Hebrew version of the MDS-UPDRS meets the requirements to be designated as the Official Hebrew Version of the MDS-UPDRS.

dc.identifier

S1353-8020(17)30341-3

dc.identifier.issn

1353-8020

dc.identifier.issn

1873-5126

dc.identifier.uri

https://hdl.handle.net/10161/19152

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Parkinsonism & related disorders

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10.1016/j.parkreldis.2017.09.012

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Humans

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Parkinson Disease

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Severity of Illness Index

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Language

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Translating

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Adult

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Aged

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Aged, 80 and over

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Middle Aged

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Israel

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Female

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Male

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Mental Status and Dementia Tests

dc.title

Validation of the Hebrew version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale.

dc.type

Journal article

duke.contributor.orcid

Luo, Sheng T|0000-0003-4214-5809

pubs.begin-page

7

pubs.end-page

12

pubs.organisational-group

School of Medicine

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Duke

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Duke Clinical Research Institute

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Institutes and Centers

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Biostatistics & Bioinformatics

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Basic Science Departments

pubs.publication-status

Published

pubs.volume

45

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