Hallucinogen-related disorders in a national sample of adolescents: the influence of ecstasy/MDMA use.

dc.contributor.author

Wu, Li-Tzy

dc.contributor.author

Ringwalt, Christopher L

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Weiss, Roger D

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Blazer, Dan G

dc.date.accessioned

2020-02-03T05:58:40Z

dc.date.available

2020-02-03T05:58:40Z

dc.date.issued

2009-09

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2020-02-03T05:58:39Z

dc.description.abstract

To present the prevalence and correlates of hallucinogen use disorders (HUDs: abuse or dependence) and subthreshold dependence.The study sample included adolescents aged 12-17 years (N=55,286) who participated in the National Survey on Drug Use and Health (2004-2006). Data were collected with a combination of computer-assisted personal interviewing and audio computer-assisted self-interviewing.The overall prevalence of HUDs among adolescents was low (<1%). However, more than one in three (38.5%) MDMA users and nearly one in four (24.1%) users of other hallucinogens reported HUD symptoms. MDMA users were more likely than users of other hallucinogens to meet criteria for hallucinogen dependence: 11% (95% confidence interval [CI]: 8.24-14.81) vs. 3.5% (95% CI: 2.22-5.43). Compared with hallucinogen use only, subthreshold dependence was associated with being female (adjusted odds ratio [AOR]=1.8 [95% CI: 1.08-2.89]), ages 12-13 years (AOR=3.4 [1.64-7.09]), use of hallucinogens > or = 52 days (AOR=2.4 [1.66-6.92]), and alcohol use disorder (AOR=1.8 [1.21-2.77]). Compared with subthreshold dependence, abuse was associated with mental health service use (AOR=1.7 [1.00-3.00]) and opioid use disorder (AOR=4.9 [1.99-12.12]); dependence was associated with MDMA use (AOR=2.2 [1.05-4.77]), mental health service use (AOR=2.9 [1.34-6.06]), and opioid use disorder (AOR=2.6 [1.01-6.90]). MDMA users had a higher prevalence of most other substance use disorders than users of non-hallucinogen drugs.Adolescent MDMA users appear to be particularly at risk for exhibiting hallucinogen dependence and other substance use disorders.

dc.identifier

S0376-8716(09)00155-0

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0376-8716

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1879-0046

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https://hdl.handle.net/10161/20003

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Drug and alcohol dependence

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10.1016/j.drugalcdep.2009.04.014

dc.subject

Humans

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Substance-Related Disorders

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N-Methyl-3,4-methylenedioxyamphetamine

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Hallucinogens

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Mental Health

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Psychiatric Status Rating Scales

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Crime

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Socioeconomic Factors

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Students

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Adolescent

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Child

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Ethnic Groups

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United States

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Female

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Male

dc.title

Hallucinogen-related disorders in a national sample of adolescents: the influence of ecstasy/MDMA use.

dc.type

Journal article

duke.contributor.orcid

Wu, Li-Tzy|0000-0002-5909-2259

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156

pubs.end-page

166

pubs.issue

1-2

pubs.organisational-group

School of Medicine

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Duke

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Center for Child and Family Policy

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Sanford School of Public Policy

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Duke Clinical Research Institute

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Institutes and Centers

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Duke Institute for Brain Sciences

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University Institutes and Centers

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Institutes and Provost's Academic Units

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Psychiatry & Behavioral Sciences, Social and Community Psychiatry

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Psychiatry & Behavioral Sciences

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Clinical Science Departments

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Medicine, General Internal Medicine

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Medicine

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Center for the Study of Aging and Human Development

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Family Medicine and Community Health

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Psychiatry & Behavioral Sciences, Geriatric Behavioral Health

pubs.publication-status

Published

pubs.volume

104

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