Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement.

dc.contributor.author

Gambaro, Giovanni

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Croppi, Emanuele

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Coe, Fredric

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Lingeman, James

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Moe, Orson

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Worcester, Elen

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Buchholz, Noor

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Bushinsky, David

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Curhan, Gary C

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Ferraro, Pietro Manuel

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Fuster, Daniel

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Goldfarb, David S

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Heilberg, Ita Pfeferman

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Hess, Bernard

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Lieske, John

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Marangella, Martino

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Milliner, Dawn

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Preminger, Glen M

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Reis Santos, Jose' Manuel

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Sakhaee, Khashayar

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Sarica, Kemal

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Siener, Roswitha

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Strazzullo, Pasquale

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Williams, James C

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Consensus Conference Group

dc.date.accessioned

2022-08-01T15:38:43Z

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2022-08-01T15:38:43Z

dc.date.issued

2016-12

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2022-08-01T15:38:41Z

dc.description.abstract

Background

Recently published guidelines on the medical management of renal stone disease did not address relevant topics in the field of idiopathic calcium nephrolithiasis, which are important also for clinical research.

Design

A steering committee identified 27 questions, which were proposed to a faculty of 44 experts in nephrolithiasis and allied fields. A systematic review of the literature was conducted and 5216 potentially relevant articles were selected; from these, 407 articles were deemed to provide useful scientific information. The Faculty, divided into working groups, analysed the relevant literature. Preliminary statements developed by each group were exhaustively discussed in plenary sessions and approved.

Results

Statements were developed to inform clinicians on the identification of secondary forms of calcium nephrolithiasis and systemic complications; on the definition of idiopathic calcium nephrolithiasis; on the use of urinary tests of crystallization and of surgical observations during stone treatment in the management of these patients; on the identification of patients warranting preventive measures; on the role of fluid and nutritional measures and of drugs to prevent recurrent episodes of stones; and finally, on the cooperation between the urologist and nephrologist in the renal stone patients.

Conclusions

This document has addressed idiopathic calcium nephrolithiasis from the perspective of a disease that can associate with systemic disorders, emphasizing the interplay needed between urologists and nephrologists. It is complementary to the American Urological Association and European Association of Urology guidelines. Future areas for research are identified.
dc.identifier

10.1007/s40620-016-0329-y

dc.identifier.issn

1121-8428

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1724-6059

dc.identifier.uri

https://hdl.handle.net/10161/25547

dc.language

eng

dc.publisher

Springer Science and Business Media LLC

dc.relation.ispartof

Journal of nephrology

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10.1007/s40620-016-0329-y

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Consensus Conference Group

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Humans

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Recurrence

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Calcium

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Urinalysis

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Treatment Outcome

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Crystallization

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Risk Factors

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Predictive Value of Tests

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Interdisciplinary Communication

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Consensus

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Patient Care Team

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Nephrolithiasis

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Secondary Prevention

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Biomarkers

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Nephrologists

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Urologists

dc.title

Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement.

dc.type

Journal article

duke.contributor.orcid

Preminger, Glen M|0000-0003-4287-602X

pubs.begin-page

715

pubs.end-page

734

pubs.issue

6

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Duke

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School of Medicine

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Clinical Science Departments

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Surgery

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Surgery, Urology

pubs.publication-status

Published

pubs.volume

29

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