Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study.

Lunyera, Joseph

Stanifer, John W

Ingabire, Prossie

Etolu, Wilson

Bagasha, Peace

Egger, Joseph R

Patel, Uptal D

Mutungi, Gerald

Kalyesubula, Robert

England

2017-12-13T16:38:27Z

2017-12-13T16:38:27Z

2016-02-16

BACKGROUND: Despite the increasing prevalence of chronic kidney disease (CKD) in sub-Saharan Africa, few community-based screenings have been conducted in Uganda. Opportunities to improve the management of CKD in sub-Saharan Africa are limited by low awareness, inadequate access, poor recognition, and delayed presentation for clinical care. Therefore, the Uganda Kidney Foundation engaged key stakeholders in performing a screening event on World Kidney Day. METHODS: We conducted a cross-sectional pilot study in March 2013 from a convenience sample of adult, urban residents in Kampala, Uganda. We advertised the event using radio and television announcements, newspapers, billboards, and notice boards at public places, such as places of worship. Subsequently, we screened for proteinuria, hypertension, fasting glucose impairment, and obesity in a central and easily-accessible location. RESULTS: We enrolled 141 adults most of whom were female (57 %), young (64 %; 18-39 years), and had a professional occupation (52 %). The prevalence of proteinuria (13 %; 95 % confidence interval [CI] 7-19 %), hypertension (38 %; 95 % CI 31-47 %), and impaired fasting glucose (13 %; 95 % CI 9-20 %) were high in this study population. Proteinuria was most prevalent among young (18-39 years) adults (n = 14; 16 %) and among those who reported a history of alcohol intake (n = 10; 32 %). CONCLUSIONS: The prevalence of proteinuria was high among a convenience sample of urban residents in a sub-Saharan African setting. These results represent an important effort by the Ugandan Kidney Foundation to increase awareness and recognition of CKD, and they will help formulate additional epidemiological studies on NCDs in Uganda which are urgently needed and now feasible.

https://www.ncbi.nlm.nih.gov/pubmed/26879636

10.1186/s13104-016-1897-6

1756-0500

https://hdl.handle.net/10161/15877

eng

Springer Science and Business Media LLC

BMC Res Notes

10.1186/s13104-016-1897-6

Adolescent

Adult

Blood Glucose

Cross-Sectional Studies

Fasting

Female

Humans

Hypertension

Male

Pilot Projects

Prevalence

Proteinuria

Uganda

Young Adult

Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study.

Journal article

Lunyera, Joseph|0000-0002-9350-320X

Stanifer, John W|0000-0001-6379-300X

https://www.ncbi.nlm.nih.gov/pubmed/26879636

97

Clinical Science Departments

Duke

Duke Clinical Research Institute

Institutes and Centers

Institutes and Provost's Academic Units

Medicine

Medicine, General Internal Medicine

Medicine, Nephrology

Pediatrics

Pediatrics, Nephrology

School of Medicine

Staff

Temp group - logins allowed

Published online

9