Cost-effectiveness of lumbar discectomy and single-level fusion for spondylolisthesis: experience with the NeuroPoint-SD registry.

dc.contributor.author

Mummaneni, Praveen V

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Whitmore, Robert G

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Curran, Jill N

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Ziewacz, John E

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Wadhwa, Rishi

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Shaffrey, Christopher I

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Asher, Anthony L

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Heary, Robert F

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Cheng, Joseph S

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Hurlbert, R John

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Douglas, Andrea F

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Smith, Justin S

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Malhotra, Neil R

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Dante, Stephen J

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Magge, Subu N

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Kaiser, Michael G

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Abbed, Khalid M

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Resnick, Daniel K

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Ghogawala, Zoher

dc.date.accessioned

2023-08-29T23:04:52Z

dc.date.available

2023-08-29T23:04:52Z

dc.date.issued

2014-06

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2023-08-29T23:04:52Z

dc.description.abstract

Object

There is significant practice variation and uncertainty as to the value of surgical treatments for lumbar spine disorders. The authors' aim was to establish a multicenter registry to assess the efficacy and costs of common lumbar spinal procedures by using prospectively collected outcomes.

Methods

An observational prospective cohort study was completed at 13 academic and community sites. Patients undergoing single-level fusion for spondylolisthesis or single-level lumbar discectomy were included. The 36-Item Short Form Health Survey (SF-36) and Oswestry Disability Index (ODI) data were obtained preoperatively and at 1, 3, 6, and 12 months postoperatively. Power analysis estimated a sample size of 160 patients: lumbar disc (125 patients) and lumbar listhesis (35 patients). The quality-adjusted life year (QALY) data were calculated using 6-dimension utility index scores. Direct costs and complication costs were estimated using Medicare reimbursement values from 2011, and indirect costs were estimated using the human capital approach with the 2011 US national wage index. Total costs equaled $14,980 for lumbar discectomy and $43,852 for surgery for lumbar spondylolisthesis.

Results

There were 198 patients enrolled over 1 year. The mean age was 46 years (49% female) for lumbar discectomy (n = 148) and 58.1 years (60% female) for lumbar spondylolisthesis (n = 50). Ten patients with disc herniation (6.8%) and 1 with listhesis (2%) required repeat operation at 1 year. The overall 1-year follow-up rate was 88%. At 30 days, both lumbar discectomy and single-level fusion procedures were associated with significant improvements in ODI, visual analog scale, and SF-36 scores (p = 0.0002), which persisted at the 1-year evaluation (p < 0.0001). By 1 year, more than 80% of patients in each cohort who were working preoperatively had returned to work. Lumbar discectomy was associated with a gain of 0.225 QALYs over the 1-year study period ($66,578/QALY gained). Lumbar spinal fusion for Grade I listhesis was associated with a gain of 0.195 QALYs over the 1-year study period ($224,420/QALY gained).

Conclusions

This national spine registry demonstrated successful collection of high-quality outcomes data for spinal procedures in actual practice. These data are useful for demonstrating return to work and cost-effectiveness following surgical treatment of single-level lumbar disc herniation or spondylolisthesis. One-year cost per QALY was obtained, and this cost per QALY is expected to improve further by 2 years. This work sets the stage for real-world analysis of the value of health interventions.
dc.identifier.issn

1092-0684

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1092-0684

dc.identifier.uri

https://hdl.handle.net/10161/28800

dc.language

eng

dc.publisher

Journal of Neurosurgery Publishing Group (JNSPG)

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Neurosurgical focus

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10.3171/2014.3.focus1450

dc.subject

Lumbar Vertebrae

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Humans

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Spondylolisthesis

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Spinal Fusion

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Diskectomy

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Registries

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Cohort Studies

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Follow-Up Studies

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Prospective Studies

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Adult

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Middle Aged

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Cost-Benefit Analysis

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Female

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Male

dc.title

Cost-effectiveness of lumbar discectomy and single-level fusion for spondylolisthesis: experience with the NeuroPoint-SD registry.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

E3

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6

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

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Neurosurgery

pubs.publication-status

Published

pubs.volume

36

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