The trials and tribulations of enrolling couples in a randomized, controlled trial: a self-management program for hyperlipidemia as a model.
dc.contributor.author | Voils, Corrine I | |
dc.contributor.author | Yancy, William S | |
dc.contributor.author | Weinberger, Morris | |
dc.contributor.author | Bolton, Jamiyla | |
dc.contributor.author | Coffman, Cynthia J | |
dc.contributor.author | Jeffreys, Amy | |
dc.contributor.author | Oddone, Eugene Z | |
dc.contributor.author | Bosworth, Hayden B | |
dc.date.accessioned | 2024-02-01T16:57:18Z | |
dc.date.available | 2024-02-01T16:57:18Z | |
dc.date.issued | 2011-07 | |
dc.description.abstract | ObjectiveCapitalizing on spousal support may enhance the effectiveness of interventions for chronic disease management. However, couples-based interventions present logistical challenges. We describe our experience and lessons learned while recruiting couples into the Couples Partnering for Lipid-Enhancing Strategies (CouPLES) trial.MethodsThis trial seeks to reduce serum low-density lipoprotein cholesterol levels using a couples-based intervention designed to help patients engage in self-management behaviors. We proposed enrolling 250 couples over 13 months.ResultsDue to practical challenges that we encountered, recruitment and enrollment lasted 21 months. Those challenges included: travel to study site; effectively marketing the study; participant burden; and establishing eligibility criteria. By modifying our protocol to address these challenges, the recruitment rate increased from 12 to 33%.ConclusionIn the absence of trials identifying the most effective recruitment strategies, investigators may need to experiment, amending their protocol intermittently until target enrollment numbers are reached. The lessons we present may help researchers conducting couples-based interventions develop more effective protocols.Practice implicationsTo achieve target enrollment numbers, researchers conducting couples-based interventions should consider minimizing travel to the study site; carefully crafting recruitment materials; budgeting more for participant incentives and staff effort; and limiting exclusion criteria. These practices may also enhance retention. | |
dc.identifier | S0738-3991(10)00364-2 | |
dc.identifier.issn | 0738-3991 | |
dc.identifier.issn | 1873-5134 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | Elsevier BV | |
dc.relation.ispartof | Patient education and counseling | |
dc.relation.isversionof | 10.1016/j.pec.2010.06.005 | |
dc.rights.uri | ||
dc.subject | Humans | |
dc.subject | Self Care | |
dc.subject | Family Characteristics | |
dc.subject | Spouses | |
dc.subject | Research Design | |
dc.subject | Patient Selection | |
dc.subject | Social Support | |
dc.subject | Aged | |
dc.subject | Middle Aged | |
dc.subject | Female | |
dc.subject | Male | |
dc.subject | Cholesterol, LDL | |
dc.subject | Randomized Controlled Trials as Topic | |
dc.title | The trials and tribulations of enrolling couples in a randomized, controlled trial: a self-management program for hyperlipidemia as a model. | |
dc.type | Journal article | |
duke.contributor.orcid | Coffman, Cynthia J|0000-0002-4554-1463 | |
duke.contributor.orcid | Bosworth, Hayden B|0000-0001-6188-9825 | |
pubs.begin-page | 33 | |
pubs.end-page | 40 | |
pubs.issue | 1 | |
pubs.organisational-group | Duke | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Faculty | |
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Clinical Science Departments | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Biostatistics & Bioinformatics | |
pubs.organisational-group | Medicine | |
pubs.organisational-group | Psychiatry & Behavioral Sciences | |
pubs.organisational-group | Medicine, General Internal Medicine | |
pubs.organisational-group | Duke Cancer Institute | |
pubs.organisational-group | Duke Clinical Research Institute | |
pubs.organisational-group | Institutes and Provost's Academic Units | |
pubs.organisational-group | Center for the Study of Aging and Human Development | |
pubs.organisational-group | Initiatives | |
pubs.organisational-group | Duke Science & Society | |
pubs.organisational-group | Population Health Sciences | |
pubs.organisational-group | Duke Innovation & Entrepreneurship | |
pubs.organisational-group | Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences | |
pubs.organisational-group | Duke - Margolis Center For Health Policy | |
pubs.organisational-group | Biostatistics & Bioinformatics, Division of Biostatistics | |
pubs.publication-status | Published | |
pubs.volume | 84 |
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