The increase in biological safety regulations and/or guidelines regarding personnel
and facilities in high containment laboratories demands constant vigilance by biological
safety professionals responsible for safety in these environments. Safety professionals
have been faced with legislative compliance issues in the past and have developed
effective management methods to cope with the demands of these requirements. Examples
include the impact of the National Institutes of Health (NIH) recombinant DNA (rDNA)
Guidelines and the Occupational Safety and Health Administration's (OSHA) Bloodborne
Pathogens Standard. This chapter will attempt to describe seven successful strategies
for management of regulatory compliance in research that are based on an overall philosophy
of developing a “culture of safety”. Strategies range from interactive involvement
with administration and research staff to biological safety professional development.
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