Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling
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Published Version (Please cite this version)10.1186/s12964-019-0410-y
Publication InfoChen, Ming; Nath, Disharee; Li, Xiang; Mondragon, Claudia; Post, Dawn; White, Julie R; ... Kotula, Leszek (2019). Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling. Cell Communication and Signaling, 17(1). 10.1186/s12964-019-0410-y. Retrieved from https://hdl.handle.net/10161/19322.
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Assistant Professor in Pathology
Our laboratory is interested in understanding the molecular and genetic events underlying cancer progression and metastasis. The focus of our work is a series of genetically engineered mouse models that faithfully recapitulate human disease. Using a combination of mouse genetics, omics technologies, cross-species analyses and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving metastatic cancer progression, with a long