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Improved Dysphagia Outcomes in Anchored Spacers Versus Plate-Screw Systems in Anterior Cervical Discectomy and Fusion: A Systematic Review

dc.contributor.author Gabr, Mostafa A
dc.contributor.author Touko, Elisabeth
dc.contributor.author Yadav, Amol P
dc.contributor.author Karikari, Isaac
dc.contributor.author Goodwin, C Rory
dc.contributor.author Groff, Michael W
dc.contributor.author Ramirez, Luis
dc.contributor.author Abd-El-Barr, Muhammad M
dc.date.accessioned 2020-01-25T20:39:12Z
dc.date.available 2020-01-25T20:39:12Z
dc.identifier.issn 2192-5682
dc.identifier.issn 2192-5690
dc.identifier.uri https://hdl.handle.net/10161/19776
dc.description.abstract <jats:sec><jats:title>Study Design:</jats:title><jats:p> Systematic review and meta-analysis. </jats:p></jats:sec><jats:sec><jats:title>Objective:</jats:title><jats:p> To perform a systematic review of clinical outcomes between stand-alone anchored spacers and traditional cages with plate fixation for dysphagia and pseudoarthrosis using data from clinical trials. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Our search protocol was added to PROSPERO register and systematic review using PRISMA method was performed. Then, we systematically searched for studies addressing stand-alone anchored spacers in patients who underwent ACDF. Mean Neck Disability Index (NDI), dysphagia incidence % (Dinc%), and Swallowing–Quality of Life (SQOL) scores during preoperative, immediate postoperative and last follow-up visits were extracted. Chi-square and analysis of variance (ANOVA) tests were used for statistical comparisons ( P ≤ .05). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> The initial search generated 506 articles in CENTRAL and 40 articles in MEDLINE. Finally, 14 articles were included. Total number of patients was 1173 (583 anchored stand-alone and 590 plate). Dinc% scores were statistically significantly lower in the stand-alone anchored spacer compared to the plate-screw construct ( P ≤ .05). ANOVA showed no statistically significant difference in the comparisons of SQOL. On the other hand, NDI scores were statistically significantly lower in baseline of stand-alone anchored spacer and the plate-screw construct compared with both immediate postoperative and last follow-up visits ( P ≤ .05). </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> Our study results revealed that the stand-alone anchored spacers were associated with less dysphagia in the immediate and last follow-up. </jats:p></jats:sec>
dc.language en
dc.publisher SAGE Publications
dc.relation.ispartof Global Spine Journal
dc.relation.isversionof 10.1177/2192568219895266
dc.title Improved Dysphagia Outcomes in Anchored Spacers Versus Plate-Screw Systems in Anterior Cervical Discectomy and Fusion: A Systematic Review
dc.type Journal article
duke.contributor.id Gabr, Mostafa A|0501606
duke.contributor.id Yadav, Amol P|0480720
duke.contributor.id Karikari, Isaac|0293374
duke.contributor.id Goodwin, C Rory|0791318
duke.contributor.id Abd-El-Barr, Muhammad M|0791319
dc.date.updated 2020-01-25T20:39:11Z
pubs.begin-page 219256821989526
pubs.end-page 219256821989526
pubs.organisational-group Staff
pubs.organisational-group Duke
pubs.organisational-group Neurosurgery
pubs.organisational-group Clinical Science Departments
pubs.organisational-group School of Medicine
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Radiation Oncology
pubs.publication-status Published online
duke.contributor.orcid Gabr, Mostafa A|0000-0003-2058-2098
duke.contributor.orcid Yadav, Amol P|0000-0002-4913-8006
duke.contributor.orcid Goodwin, C Rory|0000-0002-6540-2751
duke.contributor.orcid Abd-El-Barr, Muhammad M|0000-0001-7151-2861


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