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Crosstalk rejection in full-field optical coherence tomography using spatially incoherent illumination with a partially coherent source

dc.contributor.author Dhalla, Al-Hafeez
dc.contributor.author Migacz, Justin V
dc.contributor.author Izatt, Joseph A
dc.date.accessioned 2011-06-21T17:27:41Z
dc.date.issued 2010-05-03
dc.identifier.issn 1605-7422
dc.identifier.uri https://hdl.handle.net/10161/4221
dc.description.abstract The recent advent of ultra high frame rate cameras gives rise to the possibility of constructing swept source full-field OCT systems with achievable volume rates approaching 10Hz and net A-scan rates approaching 10MHz. Unfortunately, when illuminated with partially coherent light, full-field OCT in turbid media suffers resolution and SNR degradation from coherent multiple scattering, a phenomenon commonly referred to as crosstalk. As a result, most FFOCT systems employ thermal sources, which provide spatially incoherent illumination to achieve crosstalk rejection. However, these thermal sources preclude the use of swept source lasers. In this work, we demonstrate the use of a carefully configured FFOCT system employing multimode fiber in the illumination arm to reduce the spatial coherence of a partially coherent source. By reducing the coherence area below the system resolution, the illumination becomes effectively spatially incoherent and crosstalk is largely rejected. We compare FFOCT images of a USAF test chart positioned beneath both transparent and turbid phantoms using both illumination schemes. © 2010 Copyright SPIE - The International Society for Optical Engineering.
dc.language.iso en_US
dc.publisher SPIE-INT SOC OPTICAL ENGINEERING
dc.relation.ispartof Progress in Biomedical Optics and Imaging - Proceedings of SPIE
dc.relation.isversionof 10.1117/12.843391
dc.title Crosstalk rejection in full-field optical coherence tomography using spatially incoherent illumination with a partially coherent source
dc.title.alternative
dc.type Journal article
duke.contributor.id Dhalla, Al-Hafeez|0304736
duke.contributor.id Izatt, Joseph A|0275014
dc.description.version Version of Record
duke.date.pubdate 2010-7-1
duke.description.issue 13
duke.description.volume 35
dc.relation.journal Optics Letters
pubs.begin-page 2305
pubs.end-page 2307
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Ophthalmology
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 7554
duke.contributor.orcid Izatt, Joseph A|0000-0003-1993-2249


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