Grading of Complications After Cervical Deformity-corrective Surgery: Are Existing Classification Systems Applicable?

dc.contributor.author

Bortz, Cole A

dc.contributor.author

Passias, Peter G

dc.contributor.author

Segreto, Frank A

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Horn, Samantha R

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Lafage, Renaud

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Smith, Justin S

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Line, Breton G

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Mundis, Gregory M

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Kelly, Michael P

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Park, Paul

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Sciubba, Daniel M

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Hamilton, D Kojo

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Gum, Jeffrey L

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Burton, Douglas C

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Hart, Robert A

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Schwab, Frank J

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Bess, Shay

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Shaffrey, Christopher

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Klineberg, Eric O

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International Spine Study Group

dc.date.accessioned

2023-06-20T13:11:52Z

dc.date.available

2023-06-20T13:11:52Z

dc.date.issued

2019-07

dc.date.updated

2023-06-20T13:11:51Z

dc.description.abstract

Study design

This is a retrospective review of prospective multicenter cervical deformity (CD) database.

Objective

Assess the impact of complication type and Clavien complication (Cc) grade on clinical outcomes of surgical CD patients BACKGROUND:: Validated for general surgery, the Clavien-Dindo complication classification system allows for broad comparison of postoperative complications; however, the applicability of this system is unclear in CD-specific populations.

Methods

Surgical CD patients above 18 years with baseline and postoperative clinical data were included. Primary outcomes were complication type (renal, infection, cardiac, pulmonary, gastrointestinal, neurological, musculoskeletal, implant-related, radiographic, operative, wound) and Cc grade (I, II, III, IV, V). Secondary outcomes were estimated blood loss (EBL), length of stay (LOS), reoperation, and health-related quality of life (HRQL) score. The univariate analysis assessed the impact of complication type and Cc grade on improvement markers and 1-year postoperative HRQL outcomes.

Results

In total, 153 patients (61±10 y, 61% female) underwent surgery for CD (8.1±4.6 levels fused; surgical approach included 48% posterior, 18% anterior, 34% combined). Overall, 63% of patients suffered at least 1 complication. Complication breakdown by type: renal (2.0%), infection (5.2%), cardiac (7.2%), pulmonary (3.9%), gastrointestinal (2.0%), neurological (26.1%), musculoskeletal (0.0%), implant-related (3.9%), radiographic (16.3%), operative (7.8%), and wound (5.2%). Of complication types, only operative complications were associated with increased EBL (P=0.004), whereas renal, cardiac, pulmonary, gastrointestinal, neurological, radiographic, and wound infections were associated with increased LOS (P<0.050). Patients were also assessed by Cc grade: I (28%), II (14.3%), III (16.3%), IV (6.5%), and V (0.7%). Grades I and V were associated with increased EBL (both P<0.050); Cc grade V was the only complication not associated with increased LOS (P=0.610). Increasing complication severity was correlated with increased risk of reoperation (r=0.512; P<0.001), but not inferior 1-year HRQL outcomes (all P>0.05).

Conclusions

Increasing complication severity, assessed by the Clavien-Dindo classification system, was not associated with increased EBL, inpatient LOS, or inferior 1-year postoperative HRQL outcomes. Only operative complications were associated with increased EBL. These results suggest a need for modification of the Clavien system to increase applicability and utility in CD-specific populations.
dc.identifier.issn

2380-0186

dc.identifier.issn

2380-0194

dc.identifier.uri

https://hdl.handle.net/10161/28196

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

Clinical spine surgery

dc.relation.isversionof

10.1097/bsd.0000000000000748

dc.subject

International Spine Study Group

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Cervical Vertebrae

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Humans

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Postoperative Complications

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Treatment Outcome

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Length of Stay

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Reoperation

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Quality of Life

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Adult

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Female

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Male

dc.title

Grading of Complications After Cervical Deformity-corrective Surgery: Are Existing Classification Systems Applicable?

dc.type

Journal article

duke.contributor.orcid

Passias, Peter G|0000-0002-1479-4070|0000-0003-2635-2226

duke.contributor.orcid

Shaffrey, Christopher|0000-0001-9760-8386

pubs.begin-page

263

pubs.end-page

268

pubs.issue

6

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

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Clinical Science Departments

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

32

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