Automated quality control in nuclear medicine using the structured noise index.

dc.contributor.author

Nelson, Jeffrey S

dc.contributor.author

Samei, Ehsan

dc.date.accessioned

2022-10-18T17:12:11Z

dc.date.available

2022-10-18T17:12:11Z

dc.date.issued

2020-04

dc.date.updated

2022-10-18T17:12:10Z

dc.description.abstract

Purpose

Daily flood-field uniformity evaluation serves as the central element of nuclear medicine (NM) quality control (QC) programs. Uniformity images are traditionally analyzed using pixel value-based metrics, that is, integral uniformity (IU), which often fail to capture subtle structure and patterns caused by changes in gamma camera performance, requiring visual inspections which are subjective and time demanding. The goal of this project was to implement an advanced QC metrology for NM to effectively identify nonuniformity issues, and report issues in a timely manner for efficient correction prior to clinical use. The project involved the implementation of the program over a 2-year period at a multisite major medical institution.

Methods

Using a previously developed quantitative uniformity analysis metric, the structured noise index (SNI) [Nelson et al. (2014), \textit{J Nucl Med.}, \textbf{55}:169-174], an automated QC process was developed to analyze, archive, and report on daily NM QC uniformity images. Clinical implementation of the newly developed program ran in parallel with the manufacturer's reported IU-based QC program. The effectiveness of the SNI program was evaluated over a 21-month period using sensitivity and coefficient of variation statistics.

Results

A total of 7365 uniformity QC images were analyzed. Lower level SNI alerts were generated in 12.5% of images and upper level alerts in 1.7%. Intervention due to image quality issues occurred on 26 instances; the SNI metric identified 24, while the IU metric identified eight. The SNI metric reported five upper level alerts where no clinical engineering intervention was deemed necessary.

Conclusion

An SNI-based QC program provides a robust quantification of the performance of gamma camera uniformity. It operates seamlessly across a fleet of multiple camera models and, additionally, provides effective workflow among the clinical staff. The reliability of this process could eliminate the need for visual inspection of each image, saving valuable time, while enabling quantitative analysis of inter- and intrasystem performance.
dc.identifier.issn

1526-9914

dc.identifier.issn

1526-9914

dc.identifier.uri

https://hdl.handle.net/10161/26095

dc.language

eng

dc.publisher

Wiley

dc.relation.ispartof

Journal of applied clinical medical physics

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10.1002/acm2.12850

dc.subject

Humans

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Radionuclide Imaging

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Artifacts

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Models, Statistical

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Normal Distribution

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Reproducibility of Results

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Gamma Cameras

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Nuclear Medicine

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Fourier Analysis

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Automation

dc.subject

Quality Control

dc.subject

Pattern Recognition, Automated

dc.subject

Quality Assurance, Health Care

dc.title

Automated quality control in nuclear medicine using the structured noise index.

dc.type

Journal article

duke.contributor.orcid

Nelson, Jeffrey S|0000-0001-6490-8008

duke.contributor.orcid

Samei, Ehsan|0000-0001-7451-3309

pubs.begin-page

80

pubs.end-page

86

pubs.issue

4

pubs.organisational-group

Duke

pubs.organisational-group

Pratt School of Engineering

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School of Medicine

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Trinity College of Arts & Sciences

pubs.organisational-group

Staff

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Clinical Science Departments

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Biomedical Engineering

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Electrical and Computer Engineering

pubs.organisational-group

Radiology

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Physics

pubs.organisational-group

Duke University Medical Physics Graduate Program

pubs.publication-status

Published

pubs.volume

21

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