Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.

dc.contributor.author

Truong, Trong-Kha

dc.contributor.author

Song, Allen W

dc.contributor.author

Chen, Nan-Kuei

dc.coverage.spatial

United States

dc.date.accessioned

2016-05-10T16:13:01Z

dc.date.issued

2015

dc.description.abstract

In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase the signal-to-noise ratio (SNR). However, eddy currents induced by the diffusion-sensitizing gradients can often lead to a shift of the echo in k-space, resulting in three distinct types of artifacts in partial-Fourier DTI. Here, we present an improved DTI acquisition and reconstruction scheme, capable of generating high-quality and high-SNR DTI data without eddy current-induced artifacts. This new scheme consists of three components, respectively, addressing the three distinct types of artifacts. First, a k-space energy-anchored DTI sequence is designed to recover eddy current-induced signal loss (i.e., Type 1 artifact). Second, a multischeme partial-Fourier reconstruction is used to eliminate artificial signal elevation (i.e., Type 2 artifact) associated with the conventional partial-Fourier reconstruction. Third, a signal intensity correction is applied to remove artificial signal modulations due to eddy current-induced erroneous T2(∗) -weighting (i.e., Type 3 artifact). These systematic improvements will greatly increase the consistency and accuracy of DTI measurements, expanding the utility of DTI in translational applications where quantitative robustness is much needed.

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/26413505

dc.identifier.eissn

2314-6141

dc.identifier.uri

https://hdl.handle.net/10161/11994

dc.language

eng

dc.publisher

Hindawi Limited

dc.relation.ispartof

Biomed Res Int

dc.relation.isversionof

10.1155/2015/185026

dc.subject

Artifacts

dc.subject

Brain

dc.subject

Diffusion Tensor Imaging

dc.subject

Fourier Analysis

dc.subject

Humans

dc.subject

Image Processing, Computer-Assisted

dc.title

Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.

dc.type

Journal article

duke.contributor.orcid

Truong, Trong-Kha|0000-0003-2699-1554

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/26413505

pubs.begin-page

185026

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Biomedical Engineering

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Duke

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Duke Institute for Brain Sciences

pubs.organisational-group

Duke-UNC Center for Brain Imaging and Analysis

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Neurobiology

pubs.organisational-group

Pratt School of Engineering

pubs.organisational-group

Psychiatry & Behavioral Sciences

pubs.organisational-group

Radiology

pubs.organisational-group

School of Medicine

pubs.organisational-group

University Institutes and Centers

pubs.publication-status

Published

pubs.volume

2015

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.pdf
Size:
3.35 MB
Format:
Adobe Portable Document Format
Description:
Published version