Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent.
| dc.contributor.author | Samei, Ehsan | |
| dc.contributor.author | Saunders, Robert S | |
| dc.contributor.author | Badea, Cristian T | |
| dc.contributor.author | Ghaghada, Ketan B | |
| dc.contributor.author | Hedlund, Laurence W | |
| dc.contributor.author | Qi, Yi | |
| dc.contributor.author | Yuan, Hong | |
| dc.contributor.author | Bentley, Rex C | |
| dc.contributor.author | Mukundan, Srinivasan | |
| dc.coverage.spatial | New Zealand | |
| dc.date.accessioned | 2018-03-13T10:39:19Z | |
| dc.date.available | 2018-03-13T10:39:19Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | A long circulating liposomal, nanoscale blood pool agent encapsulating traditional iodinated contrast agent (65 mg I/mL) was used for micro-computed tomography (CT) imaging of rats implanted with R3230AC mammary carcinoma. Three-dimensional vascular architecture of tumors was imaged at 100-micron isotropic resolution. The image data showed good qualitative correlation with pathologic findings. The approach holds promise for studying tumor angiogenesis and for evaluating anti-angiogenesis therapies. | |
| dc.identifier | ||
| dc.identifier.eissn | 1178-2013 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Future Medicine Ltd | |
| dc.relation.ispartof | Int J Nanomedicine | |
| dc.subject | angiogenesis | |
| dc.subject | breast cancer | |
| dc.subject | liposome | |
| dc.subject | micro-CT | |
| dc.subject | molecular imaging | |
| dc.subject | small animal imaging | |
| dc.subject | Animals | |
| dc.subject | Cell Line, Tumor | |
| dc.subject | Contrast Media | |
| dc.subject | Female | |
| dc.subject | Iopamidol | |
| dc.subject | Liposomes | |
| dc.subject | Mammary Neoplasms, Animal | |
| dc.subject | Mammography | |
| dc.subject | Nanoparticles | |
| dc.subject | Radiographic Image Enhancement | |
| dc.subject | Rats | |
| dc.subject | Rats, Inbred F344 | |
| dc.subject | Tomography, X-Ray Computed | |
| dc.title | Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Samei, Ehsan|0000-0001-7451-3309 | |
| duke.contributor.orcid | Badea, Cristian T|0000-0002-1850-2522 | |
| duke.contributor.orcid | Bentley, Rex C|0000-0002-4947-9150 | |
| pubs.author-url | ||
| pubs.begin-page | 277 | |
| pubs.end-page | 282 | |
| pubs.organisational-group | Biomedical Engineering | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Pathology | |
| pubs.organisational-group | Physics | |
| pubs.organisational-group | Pratt School of Engineering | |
| pubs.organisational-group | Radiology | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Trinity College of Arts & Sciences | |
| pubs.publication-status | Published | |
| pubs.volume | 4 |
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