High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot

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<jats:title>Abstract</jats:title><jats:p>We conducted a randomized controlled pilot study in infants with critical bronchiolitis (n = 63) comparing high-flow nasal cannula (HFNC, n = 35) to continuous positive airway pressure (CPAP, n = 28). The primary outcome was treatment failure, defined as the need for bilevel positive pressure ventilation or endotracheal intubation. Treatment failure occurred in 10 patients (35.7%) in the CPAP group and 13 patients (37.1%) in the HFNC group (p = 0.88). Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups (5 [4–7] days and 5 [4–8] days, p = 0.46, respectively). In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP.</jats:p>

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https://hdl.handle.net/10161/20572

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10.1055/s-0040-1709656

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Cesar, Regina Grigolli, Bibiane Ramos Pinheiro Bispo, Priscilla Helena Costa Alves Felix, Maria Carolina Caparica Modolo, Andreia Aparecida Freitas Souza, Nelson K Horigoshi and Alexandre T Rotta (n.d.). High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot. Journal of Pediatric Intensive Care. 10.1055/s-0040-1709656 Retrieved from https://hdl.handle.net/10161/20572.

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