Effect of lithotripter focal width on stone comminution in shock wave lithotripsy.

dc.contributor.author

Qin, Jun

dc.contributor.author

Simmons, W Neal

dc.contributor.author

Sankin, Georgy

dc.contributor.author

Zhong, Pei

dc.coverage.spatial

United States

dc.date.accessioned

2011-06-21T17:27:44Z

dc.date.issued

2010-04

dc.description.abstract

Using a reflector insert, the original HM-3 lithotripter field at 20 kV was altered significantly with the peak positive pressure (p(+)) in the focal plane increased from 49 to 87 MPa while the -6 dB focal width decreased concomitantly from 11 to 4 mm. Using the original reflector, p(+) of 33 MPa with a -6 dB focal width of 18 mm were measured in a pre-focal plane 15-mm proximal to the lithotripter focus. However, the acoustic pulse energy delivered to a 28-mm diameter area around the lithotripter axis was comparable ( approximately 120 mJ). For all three exposure conditions, similar stone comminution ( approximately 70%) was produced in a mesh holder of 15 mm after 250 shocks. In contrast, stone comminution produced by the modified reflector either in a 15-mm finger cot (45%) or in a 30-mm membrane holder (14%) was significantly reduced from the corresponding values (56% and 26%) produced by the original reflector (no statistically significant differences were observed between the focal and pre-focal planes). These observations suggest that a low-pressure/broad focal width lithotripter field will produce better stone comminution than its counterpart with high-pressure/narrow focal width under clinically relevant in vitro comminution conditions.

dc.description.version

Version of Record

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/20370044

dc.identifier.eissn

1520-8524

dc.identifier.uri

https://hdl.handle.net/10161/4244

dc.language

eng

dc.language.iso

en_US

dc.publisher

Acoustical Society of America (ASA)

dc.relation.ispartof

J Acoust Soc Am

dc.relation.isversionof

10.1121/1.3308409

dc.relation.journal

Journal of the Acoustical Society of America

dc.subject

Acoustics

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Calculi

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Equipment Design

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Lithotripsy

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Materials Testing

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Models, Theoretical

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Motion

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Phantoms, Imaging

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Pressure

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Time Factors

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Transducers, Pressure

dc.title

Effect of lithotripter focal width on stone comminution in shock wave lithotripsy.

dc.title.alternative
dc.type

Journal article

duke.date.pubdate

2010-4-0

duke.description.issue

4

duke.description.volume

127

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/20370044

pubs.begin-page

2635

pubs.end-page

2645

pubs.issue

4

pubs.organisational-group

Biomedical Engineering

pubs.organisational-group

Duke

pubs.organisational-group

Mechanical Engineering and Materials Science

pubs.organisational-group

Pratt School of Engineering

pubs.publication-status

Published

pubs.volume

127

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