Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis.
| dc.contributor.author | Brown, MA | |
| dc.contributor.author | Zhang, L | |
| dc.contributor.author | Levering, VW | |
| dc.contributor.author | Wu, JH | |
| dc.contributor.author | Satterwhite, LL | |
| dc.contributor.author | Brian, L | |
| dc.contributor.author | Freedman, NJ | |
| dc.contributor.author | Truskey, GA | |
| dc.date.accessioned | 2024-10-01T14:34:48Z | |
| dc.date.available | 2024-10-01T14:34:48Z | |
| dc.date.issued | 2010-11 | |
| dc.description.abstract | OBJECTIVE: To accelerate vein graft reendothelialization and reduce vein graft thrombosis by infusing human umbilical cord blood-derived endothelial cells (hCB-ECs) because loss of endothelium contributes to vein graft thrombosis and neointimal hyperplasia. RESULTS: Under steady flow conditions in vitro, hCB-ECs adhered to smooth muscle cells 2.5 to 13 times more than ECs derived from peripheral blood or human aorta (P | |
| dc.identifier | ATVBAHA.110.207076 | |
| dc.identifier.issn | 1524-4636 | |
| dc.identifier.issn | 1524-4636 | |
| dc.identifier.uri | ||
| dc.language | English | |
| dc.publisher | Ovid Technologies (Wolters Kluwer Health) | |
| dc.relation.ispartof | Arteriosclerosis, thrombosis, and vascular biology | |
| dc.relation.isversionof | 10.1161/ATVBAHA.110.207076 | |
| dc.rights.uri | ||
| dc.subject | Animals Blood Vessel Prosthesis Cells | |
| dc.subject | Cultured Endothelial Cells Endothelium | |
| dc.subject | Vascular Fetal Blood Graft Occlusion | |
| dc.subject | Vascular Humans Mice Postoperative Complications Thrombosis Veins Wound Healing cytology physiology physiology* physiopathology prevention & control* surgery* | |
| dc.title | Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Freedman, NJ|0000-0002-8593-8676 | |
| duke.contributor.orcid | Truskey, GA|0000-0002-6885-4489 | |
| pubs.begin-page | 2150 | |
| pubs.end-page | 2155 | |
| pubs.issue | 11 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Pratt School of Engineering | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Cell Biology | |
| pubs.organisational-group | Biomedical Engineering | |
| pubs.organisational-group | Civil and Environmental Engineering | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Cardiology | |
| pubs.organisational-group | University Initiatives & Academic Support Units | |
| pubs.organisational-group | University Institutes and Centers | |
| pubs.organisational-group | Duke Institute for Brain Sciences | |
| pubs.organisational-group | Initiatives | |
| pubs.organisational-group | Duke Science & Society | |
| pubs.organisational-group | Duke Regeneration Center | |
| pubs.publication-status | Published | |
| pubs.volume | 30 |
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