Refractory Cytomegalovirus Colitis Followed by <i>De Novo</i> Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation.

dc.contributor.author

Selvan, Bharathi

dc.contributor.author

Pendse, Avani A

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Zhang, Cecelia

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Cauthen, Jeffriann

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Kappus, Matthew R

dc.contributor.author

Messina, Julia A

dc.date.accessioned

2023-12-28T13:36:47Z

dc.date.available

2023-12-28T13:36:47Z

dc.date.issued

2023-12

dc.description.abstract

Cytomegalovirus (CMV) and inflammatory bowel disease (IBD) are both immune-mediated complications that affect orthotopic liver transplantation patients. In this report, we present a 60-year-old man who underwent orthotopic liver transplantation for cryptogenic cirrhosis with serologies notable for CMV-seropositive donor and seronegative recipient. His post-transplant course was initially complicated by probable refractory CMV colitis. However, his gastrointestinal symptoms persisted, eventually leading to a diagnosis of post-transplant de novo IBD. The discussion highlights theories regarding the association between CMV and IBD, a topic that has been widely debated for decades.

dc.identifier

ACGCR-23-0683

dc.identifier.issn

2326-3253

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2326-3253

dc.identifier.uri

https://hdl.handle.net/10161/29560

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

ACG case reports journal

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10.14309/crj.0000000000001232

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.subject

cytomegalovirus

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inflammatory bowel disease

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liver transplantation

dc.title

Refractory Cytomegalovirus Colitis Followed by De Novo Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation.

dc.type

Journal article

duke.contributor.orcid

Pendse, Avani A|0000-0002-9243-8047

duke.contributor.orcid

Kappus, Matthew R|0000-0003-3365-5903

duke.contributor.orcid

Messina, Julia A|0000-0001-6411-198X

pubs.begin-page

e01232

pubs.issue

12

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Medicine

pubs.organisational-group

Medicine, Infectious Diseases

pubs.publication-status

Published

pubs.volume

10

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