Recovery and survival from aging-associated diseases.

dc.contributor.author

Akushevich, Igor

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Kravchenko, Julia

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Ukraintseva, Svetlana

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Arbeev, Konstantin

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Yashin, Anatoliy I

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England

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2017-06-06T14:34:39Z

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2017-06-06T14:34:39Z

dc.date.issued

2013-08

dc.description.abstract

OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan of the US elderly population may lead to erroneous conclusions when recovery/long-term remission factors are underestimated. Using two Medicare-based population datasets, we investigated the properties of recovery from eleven age-related diseases. METHODS: Cohorts of patients who stopped visiting doctors during a five-year follow-up since disease onset were analyzed non-parametrically and using the Cox proportional hazard model resulted in estimated recovery and survival rates and evaluated the health state of recovered individuals by comparing their survival with non-recovered patients and the general population. RESULTS: Recovered individuals had lower death rates than non-recovered patients, therefore, patients who stopped visiting doctors are a healthier subcohort. However, they had higher death rates than in general population for all considered diseases, therefore the complete recovery does not occur. CONCLUSION: Properties of recovery/long-term remission among the US population of older adults with chronic diseases were uncovered and evaluated. The results allow for a better quantifiable contribution of age-related diseases to healthy life expectancy and improving forecasts of health and mortality.

dc.identifier

https://www.ncbi.nlm.nih.gov/pubmed/23707929

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S0531-5565(13)00190-3

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1873-6815

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https://hdl.handle.net/10161/14833

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eng

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Elsevier BV

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Exp Gerontol

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10.1016/j.exger.2013.05.056

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Chronic disease onset

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Long-term remission

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Medicare

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Population-based analysis

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Recovery

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Age Factors

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Aged

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Aged, 80 and over

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Cohort Studies

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Coronary Disease

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Female

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Follow-Up Studies

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Humans

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Kaplan-Meier Estimate

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Longitudinal Studies

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Male

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Medicare

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Mortality

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Neoplasms

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Proportional Hazards Models

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Recovery of Function

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Stroke

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Survival Rate

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United States

dc.title

Recovery and survival from aging-associated diseases.

dc.type

Journal article

duke.contributor.orcid

Arbeev, Konstantin|0000-0002-4195-7832

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/23707929

pubs.begin-page

824

pubs.end-page

830

pubs.issue

8

pubs.organisational-group

Center for Population Health & Aging

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Clinical Science Departments

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Duke

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Duke Cancer Institute

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Duke Population Research Center

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Duke Population Research Institute

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Institutes and Centers

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Institutes and Provost's Academic Units

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Physics

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Sanford School of Public Policy

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School of Medicine

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Social Science Research Institute

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Staff

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Surgery

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Surgery, Surgical Sciences

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Trinity College of Arts & Sciences

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University Institutes and Centers

pubs.publication-status

Published

pubs.volume

48

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