Accuracy and efficiency of image-guided radiation therapy (IGRT) for preoperative partial breast radiosurgery.

dc.contributor.author

Yoo, Sua

dc.contributor.author

O'Daniel, Jennifer

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Blitzblau, Rachel

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Yin, Fang-Fang

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Horton, Janet K

dc.date.accessioned

2022-10-03T11:09:11Z

dc.date.available

2022-10-03T11:09:11Z

dc.date.issued

2020-01

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2022-10-03T11:09:11Z

dc.description.abstract

Objective

To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery.

Methods

Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatment 3D CBCT images, (3) verification orthogonal 2D kV images, (4) treatment including mid-treatment 2D kV images (for the final 15 patients only), and (5) post-treatment orthogonal 2D kV or 3D CBCT images. Patient position was corrected at each step to align the biopsy clip and to verify surrounding soft tissue positioning.

Results

The mean combined vector magnitude shifts and standard deviations at the 5 imaging steps were (1) 0.96 ± 0.69, (2) 0.33 ± 0.40, (3) 0.05 ± 0.12, (4) 0.15 ± 0.17, and (5) 0.27 ± 0.24 in cm. The mean total IGRT time was 40.2 ± 13.2 minutes. Each step was shortened by 2 to 5 minutes with improvements implemented. Overall, improvements in the IGRT process reduced the mean total IGRT time by approximately 20 minutes. Clip visibility was improved by implementing oblique orthogonal images.

Conclusion

Multiple imaging steps confirmed accurate patient positioning. Appropriate planning and imaging strategies improved the effectiveness and efficiency of the IGRT process for preoperative partial breast radiosurgery.
dc.identifier.issn

2156-4639

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2156-4647

dc.identifier.uri

https://hdl.handle.net/10161/26031

dc.language

eng

dc.relation.ispartof

Journal of radiosurgery and SBRT

dc.subject

IGRT

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accuracy

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breast radiosurgery

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efficiency

dc.title

Accuracy and efficiency of image-guided radiation therapy (IGRT) for preoperative partial breast radiosurgery.

dc.type

Journal article

duke.contributor.orcid

O'Daniel, Jennifer|0000-0002-1705-2988

duke.contributor.orcid

Yin, Fang-Fang|0000-0002-2025-4740|0000-0003-1064-2149

pubs.begin-page

295

pubs.end-page

301

pubs.issue

4

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Institutes and Centers

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Radiation Oncology

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Duke Cancer Institute

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Duke Kunshan University

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DKU Faculty

pubs.publication-status

Published

pubs.volume

6

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