Accuracy and efficiency of image-guided radiation therapy (IGRT) for preoperative partial breast radiosurgery.
Abstract
Objective
To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery.Methods
Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatment 3D CBCT images, (3) verification orthogonal 2D kV images, (4) treatment including mid-treatment 2D kV images (for the final 15 patients only), and (5) post-treatment orthogonal 2D kV or 3D CBCT images. Patient position was corrected at each step to align the biopsy clip and to verify surrounding soft tissue positioning.Results
The mean combined vector magnitude shifts and standard deviations at the 5 imaging steps were (1) 0.96 ± 0.69, (2) 0.33 ± 0.40, (3) 0.05 ± 0.12, (4) 0.15 ± 0.17, and (5) 0.27 ± 0.24 in cm. The mean total IGRT time was 40.2 ± 13.2 minutes. Each step was shortened by 2 to 5 minutes with improvements implemented. Overall, improvements in the IGRT process reduced the mean total IGRT time by approximately 20 minutes. Clip visibility was improved by implementing oblique orthogonal images.Conclusion
Multiple imaging steps confirmed accurate patient positioning. Appropriate planning and imaging strategies improved the effectiveness and efficiency of the IGRT process for preoperative partial breast radiosurgery.Type
Department
Description
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Scholars@Duke
Sua Yoo
Patient positioning verification for radiation therapy using OBI/CBCT; Treatment planning for breast cancer radiotherapy;
Jennifer Colleen O'Daniel
Adaptive radiotherapy
Calypso
RapidArc
TBI/TSI
2D and 3D patient-specific quality assurance techniques
Fang-Fang Yin
Stereotactic radiosurgery, Stereotactic body radiation therapy, treatment planning optimization, knowledge guided radiation therapy, intensity-modulated radiation therapy, image-guided radiation therapy, oncological imaging and informatics
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