Occult <i>Talaromyces marneffei</i> Infection Unveiled by the Novel Mp1p Antigen Detection Assay.

dc.contributor.author

Ly, Vo Trieu

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Thanh, Nguyen Tat

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Thu, Nguyen Thi Mai

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Chan, Jasper

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Day, Jeremy N

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Perfect, John

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Nga, Cao Ngoc

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Vinh Chau, Nguyen Van

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Le, Thuy

dc.date.accessioned

2021-08-18T18:13:18Z

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2021-08-18T18:13:18Z

dc.date.issued

2020-11

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2021-08-18T18:13:17Z

dc.description.abstract

Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture-negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation.

dc.identifier

ofaa502

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2328-8957

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2328-8957

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https://hdl.handle.net/10161/23602

dc.language

eng

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Oxford University Press (OUP)

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Open forum infectious diseases

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10.1093/ofid/ofaa502

dc.subject

Mp1p EIA

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Penicillium marneffei

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Talaromyces marneffei

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penicilliosis

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talaromycosis

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Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay.

dc.type

Journal article

duke.contributor.orcid

Perfect, John|0000-0002-6606-9460|0000-0003-3465-5518

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Le, Thuy|0000-0002-3393-6580

pubs.begin-page

ofaa502

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11

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School of Medicine

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Molecular Genetics and Microbiology

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Duke Global Health Institute

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Medicine, Infectious Diseases

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Duke

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Basic Science Departments

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University Institutes and Centers

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Institutes and Provost's Academic Units

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Medicine

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Clinical Science Departments

pubs.publication-status

Published

pubs.volume

7

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