Tobacco smoking and depressed mood in late childhood and early adolescence.
Abstract
OBJECTIVES:This study builds on previous observations about a suspected causal association
linking tobacco smoking with depression. With prospective data, the study sheds new
light on the temporal sequencing of tobacco smoking and depressed mood in late childhood
and early adolescence. METHODS:The epidemiologic sample that was studied consisted
of 1731 youths (aged 8-9 to 13-14 years) attending public schools in a mid-Atlantic
metropolitan area, who were assessed at least twice from 1989 to 1994. A survival
analysis was used to examine the temporal relationship from antecedent tobacco smoking
to subsequent onset of depressed mood, as well as from antecedent depressed mood to
subsequent initiation of tobacco use. RESULTS:Tobacco smoking signaled a modestly
increased risk for the subsequent onset of depressed mood, but antecedent depressed
mood was not associated with a later risk of starting to smoke tobacco cigarettes.
CONCLUSIONS:This evidence is consistent with a possible causal link from tobacco smoking
to later depressed mood in late childhood and early adolescence, but not vice versa.
Type
Journal articleSubject
HumansProportional Hazards Models
Risk
Survival Analysis
Case-Control Studies
Prospective Studies
Depression
Smoking
Adolescent
Child
Mid-Atlantic Region
Female
Male
Permalink
https://hdl.handle.net/10161/20026Published Version (Please cite this version)
10.2105/ajph.89.12.1837Publication Info
Wu, LT; & Anthony, JC (1999). Tobacco smoking and depressed mood in late childhood and early adolescence. American journal of public health, 89(12). pp. 1837-1840. 10.2105/ajph.89.12.1837. Retrieved from https://hdl.handle.net/10161/20026.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
Collections
More Info
Show full item recordScholars@Duke
Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences
Education/Training: Pre- and post-doctoral training in mental health service research,
psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns
Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute
on the Design and Conduct of Randomized Clinical Trials.Director: Duke Community Based
Substance Use Disorder Research Program.Research interests: COVID-19, Opioid misuse,
Opioid overdose, Opioid use disorder

Articles written by Duke faculty are made available through the campus open access policy. For more information see: Duke Open Access Policy
Rights for Collection: Scholarly Articles
Works are deposited here by their authors, and represent their research and opinions, not that of Duke University. Some materials and descriptions may include offensive content. More info