Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial

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Published Version (Please cite this version)

10.1371/journal.pone.0207555

Publication Info

Blocker, SJ, YM Mowery, MD Holbrook, Y Qi, DG Kirsch, GA Johnson and CT Badea (n.d.). Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial. PLOS ONE, 14(4). pp. e0207555–e0207555. 10.1371/journal.pone.0207555 Retrieved from https://hdl.handle.net/10161/18307.

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Scholars@Duke

Blocker

Stephanie Blocker

Assistant Professor in Radiology
Mowery

Yvonne Marie Mowery

Butler Harris Assistant Professor in Radiation Oncology
Kirsch

David Guy Kirsch

Adjunct Professor in the Department of Radiation Oncology

My clinical interests are the multi-modality care of patients with bone and soft tissue sarcomas and developing new sarcoma therapies. My laboratory interests include utilizing mouse models of cancer to study cancer and radiation biology in order to develop new cancer therapies in the pre-clinical setting.

Badea

Cristian Tudorel Badea

Professor in Radiology

  • Our lab's research focus lies primarily in developing novel quantitative imaging systems, reconstruction algorithms and analysis methods.  My major expertise is in preclinical CT.
  • Currently, we are particularly interested in developing novel strategies for spectral CT imaging using nanoparticle-based contrast agents for theranostics (i.e. therapy and diagnostics).
  • We are also engaged in developing new approaches for multidimensional CT image reconstruction suitable to address difficult undersampling cases in cardiac and spectral CT (dual energy and photon counting) using compressed sensing and/or deep learning.



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