Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues

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2017-04-01

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Science & Technology, Life Sciences & Biomedicine, Physical Sciences, Biochemistry & Molecular Biology, Chemistry, Inorganic & Nuclear, Chemistry, SOD mimics, Alkoxyalkyl tosylates, Mn N-alkoxyalkylpyridylporphyrins, MnTnBuOE-2-PyP5+ (BMX-001), MnTTEG-2-PyP5+, FP-15, Mechanism of pyridyl nitrogen quatemization, PEROXYNITRITE DECOMPOSITION CATALYST, SOD MIMICS, OXIDATIVE-STRESS, MANGANESE-PORPHYRIN, BASIS-SETS, IN-VIVO, BIOAVAILABILITY, MNTE-2-PYP5+, CHEMISTRY, ENERGIES

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https://hdl.handle.net/10161/21193

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10.1016/j.jinorgbio.2017.01.003

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Rajic, Zrinka, Artak Tovmasyan, Otávio L de Santana, Isabelle N Peixoto, Ivan Spasojevic, Silmar A do Monte, Elizete Ventura, Júlio S Rebouças, et al. (2017). Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues. JOURNAL OF INORGANIC BIOCHEMISTRY, 169. pp. 50–60. 10.1016/j.jinorgbio.2017.01.003 Retrieved from https://hdl.handle.net/10161/21193.

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Spasojevic

Ivan Spasojevic

Associate Professor in Medicine

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