The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.
Abstract
By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high
ELISA index values are strongly predictive of Lyme disease. In children with clinical
presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive
predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease,
making a supplemental Western immunoblot potentially unnecessary.
Type
Journal articleSubject
AdolescentChild
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
Female
Humans
Lyme Disease
Male
Predictive Value of Tests
Retrospective Studies
Permalink
https://hdl.handle.net/10161/13955Published Version (Please cite this version)
10.1097/INF.0000000000000858Publication Info
(2015). The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.
Pediatr Infect Dis J, 34(11). pp. 1260-1262. 10.1097/INF.0000000000000858. Retrieved from https://hdl.handle.net/10161/13955.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
Collections
More Info
Show full item recordScholars@Duke
Paul Michael Lantos
Professor of Medicine
I am interested in the spatial epidemiology of infectious diseases. My research utilizes
geographic information systems (GIS) and geostatistical analyses to understand the
spatial and spatiotemporal distribution of diseases, and their relationship with environmental
and demographic factors. I currently have active studies evaluating the spatial distribution
of numerous domestic and international infectious diseases, including SARS-CoV-2 (COVID-19),
cytomegalovirus, influenza, and Lyme disease. A
Articles written by Duke faculty are made available through the campus open access policy. For more information see: Duke Open Access Policy
Rights for Collection: Scholarly Articles
Works are deposited here by their authors, and represent their research and opinions, not that of Duke University. Some materials and descriptions may include offensive content. More info